Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Slk19p is a centromere protein that functions to stabilize mitotic spindles.

The Journal of cell biology - 26 Jul 1999

Zeng X, Kahana J A, Silver P A, Morphew M K, McIntosh J R, Fitch I T, Carbon J, Saunders W S

Abstract excerpt

We have identified a novel centromere-associated gene product from Saccharomyces cerevisiae that plays a role in spindle assembly and stability. Strains with a deletion of SLK19 (synthetic lethal Kar3p gene) exhibit abnormally short mitotic spindles, increased numbers of astral microtubules, and require the presence of the kinesin motor Kar3p for viability. When cells are deprived of both Slk19p and Kar3p, rapid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anaphase
Share to Centromere
Share to Genes, Lethal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Kinesins

Share to Kinetochores

Share to Microtubules

Share to Orotic Acid

Share to Spindle Apparatus

Source

Open in PubMed Open full text

Identifiers

PMID: 10427094
DOI: 10.1083/jcb.146.2.415
PMCID: PMC3206577

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Slk19p is a centromere protein that functions to stabilize mitotic spindles.PMID 10427094Read ↗

Slk19p of Saccharomyces cerevisiae regulates anaphase spindle dynamics through two independent mechanisms.Semantic proximity Read ↗

The FEAR protein Slk19 restricts Cdc14 phosphatase to the nucleus until the end of anaphase, regulating its participation in mitotic exit in Saccharomyces cerevisiae.Semantic proximity Read ↗

pkl1(+)and klp2(+): Two kinesins of the Kar3 subfamily in fission yeast perform different functions in both mitosis and meiosis.Semantic proximity Read ↗

Mitotic Nuclear Envelope Breakdown and Spindle Nucleation Are Controlled by Interphase Contacts between Centromeres and the Nuclear Envelope.Semantic proximity Read ↗

The MEN mediates the effects of the spindle assembly checkpoint on Kar9-dependent spindle pole body inheritance in budding yeast.Semantic proximity Read ↗

Budding yeast Cdc20: a target of the spindle checkpoint.Semantic proximity Read ↗

Kinesins klp5(+) and klp6(+) are required for normal chromosome movement in mitosis.Semantic proximity Read ↗

Analysis of kinesin motor function at budding yeast kinetochores.Semantic proximity Read ↗

Genome-wide synthetic lethal screens identify an interaction between the nuclear envelope protein, Apq12p, and the kinetochore in Saccharomyces cerevisiae.Semantic proximity Read ↗

A pathway containing the Ipl1/aurora protein kinase and the spindle midzone protein Ase1 regulates yeast spindle assembly.Semantic proximity Read ↗

The Cik1/Kar3 motor complex is required for the proper kinetochore-microtubule interaction after stressful DNA replication.Semantic proximity Read ↗

Mitotic motors in Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.