Article
Mannose-binding lectin alleles in sub-Saharan Africans and relation with susceptibility to infections.
Genes and immunity - 1 Jul 2003
Mombo L E, Lu C Y, Ossari S, Bedjabaga I, Sica L, Krishnamoorthy R, Lapoumeroulie C
Abstract excerpt
Mannose-binding lectin (MBL) plays an important role in the early stages of primary infections and during the decay of maternal antibodies in infants. Various studies have looked at the relation between serum MBL concentrations, MBL gene alterations and susceptibility to infections. We investigated the distribution of variant MBL alleles in 626 unrelated adults from sub-Saharan African countries and looked for a...
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