Article
Genetic heterogeneity within ulcerative colitis determined by an interleukin-1 receptor antagonist gene polymorphism and antineutrophil cytoplasmic antibodies.
European journal of gastroenterology & hepatology - 1 Apr 1999
Papo M, Quer J C, Gutierrez C, Broch M, Casellas F, Pastor R M, Olona M, Richart C
Abstract excerpt
BACKGROUND: Although there is strong evidence implicating genetic predisposition in the pathogenesis of the chronic inflammatory bowel diseases, the number and identity of susceptibility genes remain uncertain. Cytokine genes are tentative candidate loci, but data regarding association studies in different populations are conflicting. AIMS: To determine potential associations of interleukin-1 receptor antagonist...
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