Article
Inflammatory bowel disease: the role of inflammatory cytokine gene polymorphisms.
Mediators of inflammation - 1 Jun 2004
Balding Joanna, Livingstone Wendy J, Conroy Judith, Mynett-Johnson Lesley, Weir Donald G, Mahmud Nasir, Smith Owen P
Abstract excerpt
The mechanisms responsible for development of inflammatory bowel disease (IBD) have not been fully elucidated, although the main cause of disease pathology is attributed to up-regulated inflammatory processes. The aim of this study was to investigate frequencies of polymorphisms in genes encoding pro-inflammatory and anti-inflammatory markers in IBD patients and controls. We determined genotypes of patients with...
Topics
- Adult
- Age of Onset
- Base Sequence
- Cytokines
- DNA Primers
- Female
- Genotype
- Humans
- Inflammation
- Inflammatory Bowel Diseases
- Interleukin-1
