Article
Pro- and anti-inflammatory cytokine gene single-nucleotide polymorphisms in inflammatory bowel disease.
International journal of immunogenetics - 1 Feb 2015
López-Hernández R, Valdés M, Campillo J A, Martínez-García P, Salama H, Bolarin J M, Martínez H, Moya-Quiles M R, Minguela A, Sánchez-Torres A, Botella C, Salgado G, Miras M, Carballo F, Muro M
Abstract excerpt
Anti-inflammatory cytokines have an important role in disease, tumour and transplant processes. Alterations in the regulation of several cytokines have been implicated in a variety of inflammatory disorders, including IBD (inflammatory bowel disease) [Crohn's disease (CD) and ulcerative colitis (UC)]. Cytokine polymorphisms are also known to affect the level of gene expression. Thus, the aim of this study was to...
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