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Article

Five genetic markers in the interleukin 1 family in relation to inflammatory bowel disease.

Gut - 1 Jul 1998

Stokkers P C, van Aken B E, Basoski N, Reitsma P H, Tytgat G N, van Deventer S J

Abstract excerpt

BACKGROUND: An imbalance between the proinflammatory cytokine interleukin 1 beta (IL-1 beta) and the anti-inflammatory cytokine IL-1 receptor antagonist (IL-1ra) has been postulated as a pathogenic factor in inflammatory bowel disease (IBD). AIMS: To study allelic frequencies of novel polymorphisms in the genes for IL-1 beta and IL-1ra in patients with IBD and to assess the relation between ex vivo cytokine...

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Identifiers

PMID: 9771403
DOI: 10.1136/gut.43.1.33
PMCID: PMC1727194

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Source receipt: pubmed, retrieved 7 Sept 2026.

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