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Article

Single nucleotide polymorphism in the tumor necrosis factor-alpha gene affects inflammatory bowel diseases risk.

World journal of gastroenterology - 7 Aug 2008

Ferguson Lynnette R, Huebner Claudia, Petermann Ivonne, Gearry Richard B, Barclay Murray L, Demmers Pieter, McCulloch Alan, Han Dug Yeo

Abstract excerpt

AIM: To investigate the role that single nucleotide polymorphisms (SNPs) in the promoter of the tumour necrosis factor-alpha (TNF-alpha) gene play in the risk of inflammatory bowel diseases (IBDs) in a New Zealand population, in the context of international studies. METHODS: DNA samples from 388 patients with Crohn's disease (CD), 405 ulcerative colitis (UC), 27 indeterminate colitis (IC) and 201 randomly...

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Identifiers

PMID: 18698679
DOI: 10.3748/wjg.14.4652
PMCID: PMC2738789

Genes

TNF

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