Article
Reduction of ENU-induced transversion mutations by the isoflavone genistein in Escherichia coli.
Mutation research - 8 Aug 2001
Yang Y, Fix D
Abstract excerpt
In studies of mutagenesis induced by the carcinogen N-ethyl-N-nitrosourea (ENU) in the bacterium Escherichia coli FX-11, it was observed that G:C to A:T transitions did not require the inducible umuDC gene products, while a portion of the A:T to G:C transitions and all transversion mutations were dependent on a functional umuC gene. This observation suggested that the different base substitutions may result from...
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