Article
Comparison of the molecular characteristics of lacZ transgenic mouse mutations detected by visual and positive selection.
Mutation research - 11 Nov 1996
Jiao J, Douglas G R, Gingerich J D, Soper L M
Abstract excerpt
lacZ gene mutations in the transgenic Muta Mmouse can be detected by two different selection systems. While mutant frequencies recovered by phenyl-beta-D-galactoside (P-gal) selection are comparable with those obtained using 5-bromo-4-chloro-3-indolyl beta-D-galactopyranoside (X-gal) as substrate for beta-galactosidase, there may still be differences at the molecular level in the mutations detected by these two...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.