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Article

Dictyostelium discoideum cobB mutants show reduced heavy metal accumulation associated with gene amplification.

Molecular & general genetics : MGG - 27 Nov 1996

Hughes J E, DeLange K L, Welker D L

Abstract excerpt

Wild-type Dictyostelium discoideum cells growing on non-toxic levels of nickel chloride or cobaltous chloride accumulate 2-3.5 times as much nickel and at least 1.5 times as much cobalt as cobB mutants. The cobB trait is dominant, confers unstable cobalt and nickel resistance and is correlated with the presence of up to 50 copies of a linear extrachromosomal DNA, approximately 100 kb in length, derived from...

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Identifiers

PMID: 9003288
DOI: 10.1007/s004380050297

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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