Article

Simulating Pedigrees Ascertained for Multiple Disease-Affected Relatives

2017-12-14

Abstract excerpt

<h4>Background: </h4> Studies that ascertain families containing multiple relatives affected by disease can be useful for identification of causal, rare variants from next-generation sequencing data. <h4>Results: </h4>: We present the R package SimRVPedigree , which allows researchers to simulate pedigrees ascertained on the basis of multiple, affected relatives. By incorporating the ascertainment process in the...

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Literature Corpus work: a6021a10-c70c-566f-b32d-6db62b74324a
DOI: 10.1101/234153

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