Article

SimRVSequences: an R package to simulate genetic sequence data for pedigrees

2019-03-04

Abstract excerpt

1 <h4>Summary</h4> Family-based studies have several advantages over case-control studies for finding causal rare variants for a disease; these include increased power, smaller sample size requirements, and improved detection of sequencing errors. However, collecting suitable families and compiling their data is time-consuming and expensive. To evaluate methodology to identify causal rare variants in family-based...

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Literature Corpus work: d67becdb-164d-508d-b354-eee3f1639b31
DOI: 10.1101/534552

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