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Expression of the human <i>NRAMP1</i> gene in professional primary phagocytes: studies in blood cells and in HL-60 promyelocytic leukemia

1 Jan 1997

Abstract excerpt

In the mouse, mutations at the natural resistance-associated macrophage protein 1 (Nramp1) gene abrogate resistance to infection with antigenically unrelated intracellular parasites such as Mycobacterium, Salmonella, and Leishmania. Nramp1 expression is restricted to reticuloendothelial organs and peripheral blood leukocytes, where the protein may function as a membrane transporter of an as yet to be identified...

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PMID: 9000542
DOI: 10.1002/jlb.61.1.96

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