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Article

Nramp1 modulates iron homoeostasis in vivo and in vitro: evidence for a role in cellular iron release involving de-acidification of intracellular vesicles.

European journal of immunology - 1 Jul 2001

Biggs T E, Baker S T, Botham M S, Dhital A, Barton C H, Perry V H

Abstract excerpt

Nramp1 controls responses to infection and encodes a biallelic (G169D) macrophage-restricted divalent-cation transporter. Nramp1(D169) is phenotypically null. We demonstrate Nramp1 is implicated in iron regulation in vivo. In spleen, expression is exclusive to Nramp1(G169) strains within the red...

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PMID: 11449359
DOI: 10.1002/1521-4141(200107)31:7<2060::aid-immu2060>3.0.co;2-l

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11449359-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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