Article
Measures of variation at DNA repeat loci under a general stepwise mutation model.
Theoretical population biology - 1 Dec 1996
Kimmel M, Chakraborty R
Abstract excerpt
Polymorphisms at tandem repeat loci are caused by mutations with allele sizes occasionally altered by more than one repeat unit in both forward and backward directions. Such mutational changes may occur with asymmetric probabilities. Therefore, a one-step symmetric stepwise mutation model may not be appropriate for studying the population dynamics at all repeat loci. In this work, we evaluated the expectation and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
