Allele frequencies at microsatellite loci: the stepwise mutation model revisited.

doi:10.1093/genetics/133.3.737

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Article

Allele frequencies at microsatellite loci: the stepwise mutation model revisited.

Genetics - 1 Mar 1993

Valdes A M, Slatkin M, Freimer N B

Abstract excerpt

We summarize available data on the frequencies of alleles at microsatellite loci in human populations and compare observed distributions of allele frequencies to those generated by a simulation of the stepwise mutation model. We show that observed frequency distributions at 108 loci are consisten...

Topics

Alleles
DNA
Gene Frequency
Humans
Models, Genetic
Mutation
Repetitive Sequences, Nucleic Acid

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