Article
Population structure, stepwise mutations, heterozygote deficiency and their implications in DNA forensics.
Heredity - 1 Mar 1995
Jin L, Chakraborty R
Abstract excerpt
In a substructured population the overall heterozygote deficiency can be predicted from the number of subpopulations (s), their time of divergence (t), and the nature of the mutations. At present the true mutational mechanisms at the hypervariable DNA loci are not known. However, the two existing...
Topics
- DNA
- Forensic Medicine
- Genetics, Population
- Heterozygote
- Humans
- Minisatellite Repeats
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
