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Article

Dynamics of repeat polymorphisms under a forward-backward mutation model: within- and between-population variability at microsatellite loci.

Genetics - 1 May 1996

Kimmel M, Chakraborty R, Stivers D N, Deka R

Abstract excerpt

Suggested molecular mechanisms for the generation of new tandem repeats of simple sequences indicate that the microsatellite loci evolve via some of forward-backward mutation. We provide a mathematical basis for suggesting a measure of genetic distance between populations based on microsatellite variation. Our results indicate that such a genetic distance measure can remain proportional to the divergence time of...

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Identifiers

PMID: 8722803
DOI: 10.1093/genetics/143.1.549
PMCID: PMC1207286

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