Article
Dynamics of repeat polymorphisms under a forward-backward mutation model: within- and between-population variability at microsatellite loci.
Genetics - 1 May 1996
Kimmel M, Chakraborty R, Stivers D N, Deka R
Abstract excerpt
Suggested molecular mechanisms for the generation of new tandem repeats of simple sequences indicate that the microsatellite loci evolve via some of forward-backward mutation. We provide a mathematical basis for suggesting a measure of genetic distance between populations based on microsatellite...
Topics
- Alleles
- Biological Evolution
- DNA, Satellite
- Dinucleotide Repeats
- Genetic Variation
- Humans
- Mathematics
- Models, Genetic
- Mutation
- Poisson Distribution
- Polymorphism, Genetic
- Repetitive Sequences, Nucleic Acid
