Article
VNTR allele frequency distributions under the stepwise mutation model: a computer simulation approach.
Genetics - 1 Jul 1993
Shriver M D, Jin L, Chakraborty R, Boerwinkle E
Abstract excerpt
Variable numbers of tandem repeats (VNTRs) are a class of highly informative and widely dispersed genetic markers. Despite their wide application in biological science, little is known about their mutational mechanisms or population dynamics. The objective of this work was to investigate four summary measures of VNTR allele frequency distributions: number of alleles, number of modes, range in allele size and...
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