Gene frequency changes and a per-generation time-scale for continuous-time populations with arbitrary size variations.

Abstract excerpt

One of the most fundamental calculations needed in an examination of the effect of natural selection in a Mendelian population is to find the rate of change in continuous-time of the frequency of any allele under natural selection, and from this to find the number of generations needed for the frequency of an allele to change from one given value to another. In this paper, we analyze the presently accepted...

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