Simultaneous estimation of all the parameters of a stepwise mutation model.

doi:10.1093/genetics/150.1.487

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Article

Simultaneous estimation of all the parameters of a stepwise mutation model.

Genetics - 1 Sept 1998

Fu Y X, Chakraborty R

Abstract excerpt

Minisatellite and microsatellite are short tandemly repetitive sequences dispersed in eukaryotic genomes, many of which are highly polymorphic due to copy number variation of the repeats. Because mutation changes copy numbers of the repeat sequences in a generalized stepwise fashion, stepwise mut...

Topics

Chi-Square Distribution
Humans
Models, Genetic
Monte Carlo Method
Mutation
Polymorphism, Genetic

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