Article
A transcript exhibiting homology to endogenous rat retroviral-like elements is regulated by p53.
Oncogene - 19 Dec 1996
Gangopadhyay S B, Peacock J W, Benchimol S
Abstract excerpt
Rat embryo fibroblasts transformed with HPV-16 E7 and the Ha-ras oncogene (ER clones) fall into two distinct groups based on their endogenous p53 status, wild-type or mutant. We have taken advantage of such clones in order to study the p53 target genes by the differential display method of RNA fi...
Topics
- Animals
- Base Sequence
- Cells, Cultured
- DNA
- DNA-Binding Proteins
- Fibroblasts
- Genes, p53
- Kidney
- Mice
- Molecular Sequence Data
- Mutation
- Papillomaviridae
- RNA
- Rats
- Transcription Factors
- Transcription, Genetic
- Transfection
- Tumor Suppressor Protein p53
