Article
Differential splicing of E6 within human papillomavirus type 18 variants and functional consequences.
The Journal of general virology - 1 Sept 2005
De la Cruz-Hernández Erick, García-Carrancá Alejandro, Mohar-Betancourt Alejandro, Dueñas-González Alfonso, Contreras-Paredes Adriana, Pérez-Cardenas Enrique, Herrera-Goepfert Roberto, Lizano-Soberón Marcela
Abstract excerpt
Persistent infections of the uterine cervix with 'high-risk' human papillomavirus (HPV) are now recognized as necessary for the development of cervical cancer. Among them, HPV types 16 and 18 exhibit numerous variants associated with different risks for cervical cancer development. In this study, the questions of whether different HPV type 18 variants exhibit changes in early gene transcription and the molecular...
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