Article
CFTR-dependent membrane insertion is linked to stimulation of the CFTR chloride conductance.
The American journal of physiology - 1 Dec 1996
Takahashi A, Watkins S C, Howard M, Frizzell R A
Abstract excerpt
We examined the relation between Cl current (Icl) stimulation and cell membrane capacitance (Cm) when cystic fibrosis transmembrane conductance regulator (CFTR) was expressed in Xenopus oocytes. ICl and Cm increased in parallel when oocytes expressing CFTR were stimulated by forskolin (10 microM) and 3-isobutyl-1-methylxanthine (1 mM). The adenosine 3',5'-cyclic monophosphate (cAMP)-induced increase in surface...
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