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Article

Delta F508-CFTR channels: kinetics, activation by forskolin, and potentiation by xanthines.

The American journal of physiology - 1 May 1996

Haws C M, Nepomuceno I B, Krouse M E, Wakelee H, Law T, Xia Y, Nguyen H, Wine J J

Abstract excerpt

Trafficking, activation, and kinetics of delta F508-cystic fibrosis transmembrane conductance regulator (CFTR) and CFTR were compared in stably transduced C127I mouse mammary epithelial cells. Western blots detected a small amount of fully glycosylated delta F508-CFTR Efflux of 125I was stimulate...

Topics

1-Methyl-3-isobutylxanthine
Animals
Cell Line
Colforsin
Cyclic AMP
Cystic Fibrosis Transmembrane Conductance Regulator
Electrophysiology
Glycosylation
Iodine
Mice
Mutation
Time Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Xanthines

Source

Identifiers

PMID: 8967457
DOI: 10.1152/ajpcell.1996.270.5.C1544

Genes

CFTR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8967457-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Delta F508-CFTR channels: kinetics, activation by forskolin, and potentiation by xanthines.PMID 8967457Read ↗

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