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Article

Delta F508-CFTR channels: kinetics, activation by forskolin, and potentiation by xanthines.

The American journal of physiology - 1 May 1996

Haws C M, Nepomuceno I B, Krouse M E, Wakelee H, Law T, Xia Y, Nguyen H, Wine J J

Abstract excerpt

Trafficking, activation, and kinetics of delta F508-cystic fibrosis transmembrane conductance regulator (CFTR) and CFTR were compared in stably transduced C127I mouse mammary epithelial cells. Western blots detected a small amount of fully glycosylated delta F508-CFTR Efflux of 125I was stimulated by forskolin with the same mean effective concentration (EC50; approximately 0.5 microM) for CFTR and delta F508-CFTR...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8967457
DOI: 10.1152/ajpcell.1996.270.5.C1544

Genes

CFTR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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