Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CTLA4 alanine-17 confers genetic susceptibility to Graves' disease and to type 1 diabetes mellitus.

The Journal of clinical endocrinology and metabolism - 1 Jan 1997

Donner H, Rau H, Walfish P G, Braun J, Siegmund T, Finke R, Herwig J, Usadel K H, Badenhoop K

Abstract excerpt

The genetic susceptibility to Graves' disease and type 1 (insulin-dependent) diabetes mellitus is conferred by genes in the human leukocyte antigen region on the short arm of chromosome 6, but several other genes are presumed to determine disease susceptibility. Among those candidate genes is the cytotoxic T lymphocyte antigen 4 (CTLA4) located on chromosome 2q33 in man. We investigated the distribution of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Alleles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antigens, CD

Share to Child, Preschool

Share to Genetic Predisposition to Disease

Share to HLA-DQ Antigens

Source

Identifiers

PMID: 8989248
DOI: 10.1210/jcem.82.1.3699

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CTLA4 alanine-17 confers genetic susceptibility to Graves' disease and to type 1 diabetes mellitus.PMID 8989248Read ↗

CTLA4 Alanine-17 Confers Genetic Susceptibility to Graves' Disease and to Type 1 Diabetes MellitusSemantic proximity Read ↗

Codon 17 polymorphism of the cytotoxic T lymphocyte antigen 4 gene in Hashimoto's thyroiditis and Addison's disease.Semantic proximity Read ↗

The Development of Graves' Disease and the CTLA-4 Gene on Chromosome 2q33Semantic proximity Read ↗

The development of Graves' disease and the CTLA-4 gene on chromosome 2q33.Semantic proximity Read ↗

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease.Semantic proximity Read ↗

The codon 17 polymorphism of the CTLA4 gene in type 2 diabetes mellitus.Semantic proximity Read ↗

Association of CTLA-4 gene polymorphism with Graves' disease and ophthalmopathy in Iranian patients.Semantic proximity Read ↗

The cytotoxic T lymphocyte antigen-4 is a major Graves' disease locusSemantic proximity Read ↗

CTLA4 gene and Graves’ disease: association of Graves’ disease with the CTLA4 exon 1 and intron 1 polymorphisms, but not with the promoter polymorphismSemantic proximity Read ↗

Relation of three polymorphisms of the CTLA-4 gene in patients with Graves' disease.Semantic proximity Read ↗

Soluble CTLA-4 receptor an immunological marker of Graves' disease and severity of ophthalmopathy is associated with CTLA-4 Jo31 and CT60 gene polymorphisms.Semantic proximity Read ↗

A CTLA‐4 gene polymorphism is associated with both Graves' disease and autoimmune hypothyroidismSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.