Article
Detection by ligase chain reaction of precore mutant of hepatitis B virus.
Hepatology (Baltimore, Md.) - 1 Jan 1997
Minamitani S, Nishiguchi S, Kuroki T, Otani S, Monna T
Abstract excerpt
The clinical diagnosis of infection with the most common precore mutant of hepatitis B virus (HBV), that with a point mutation from guanine to adenine at nucleotide 83 in the precore region, is important because the disease may progress rapidly despite interferon therapy. A practical method to de...
Topics
- Adolescent
- Adult
- Aged
- Chronic Disease
- DNA, Viral
- Female
- Hepatitis B
- Hepatitis B virus
- Humans
- Liver Failure, Acute
- Male
- Middle Aged
- Mutation
- Polymerase Chain Reaction