Article
[Detection of hepatitis B virus by using polymerase chain reaction and nonradioactive DNA probes. I. Identification of mutations in the precore region by PCR-direct sequencing and ASO probe method].
Rinsho byori. The Japanese journal of clinical pathology - 1 Aug 1995
Yamashita K, Mutoh T, Takarada Y, Otsuka N, Kagawa S, Matsuoka A
Abstract excerpt
Seroconversion from hepatitis B e antigen (HBeAg) to anti-HBe antibody (anti-HBe) frequently occurs in hosts chronically infected with hepatitis B virus (HBV). Further, this phenomenon is related to a point mutation from guanine to adenine at nucleotide 83 in the precore region of HBV, which, con...
Topics
- Amino Acid Sequence
- Base Sequence
- Codon, Terminator
- Hepatitis B virus
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Polymerase Chain Reaction