Article
Biological consequences of thrombin receptor deficiency in mice.
Thrombosis and haemostasis - 1 Dec 1996
Darrow A L, Fung-Leung W P, Ye R D, Santulli R J, Cheung W M, Derian C K, Burns C L, Damiano B P, Zhou L, Keenan C M, Peterson P A, Andrade-Gordon P
Abstract excerpt
The thrombin receptor (ThrR) is a membrane-bound, G-protein-coupled receptor for the serine protease thrombin. This receptor is expressed in a wide variety of cells and tissues, and elicits a range of physiological responses associated with tissue injury, inflammation, and wound repair. To achieve a better understanding of the physiological role of the ThrR, we have employed homologous recombination to create...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.