Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Saturation mutagenesis of 5S rRNA in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Dec 2001

Smith M W, Meskauskas A, Wang P, Sergiev P V, Dinman J D

Abstract excerpt

rRNAs are the central players in the reactions catalyzed by ribosomes, and the individual rRNAs are actively involved in different ribosome functions. Our previous demonstration that yeast 5S rRNA mutants (called mof9) can impact translational reading frame maintenance showed an unexpected function for this ubiquitous biomolecule. At the time, however, the highly repetitive nature of the genes encoding rRNAs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Codon, Nonsense
Share to Frameshift Mutation
Share to Multigene Family

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Nucleic Acid Conformation

Share to Physical Chromosome Mapping

Share to Ribosomes

Share to RNA, Ribosomal, 5S

Source

Open in PubMed Open full text

Identifiers

PMID: 11713264
DOI: 10.1128/MCB.21.24.8264-8275.2001
PMCID: PMC99992

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Saturation mutagenesis of 5S rRNA in Saccharomyces cerevisiae.PMID 11713264Read ↗

Structural and functional analysis of 5S rRNA in Saccharomyces cerevisiae.Semantic proximity Read ↗

Use of mutant RNAs in studies on yeast 5S rRNA structure and function.Semantic proximity Read ↗

Ribosomal protein L5 helps anchor peptidyl-tRNA to the P-site in Saccharomyces cerevisiae.Semantic proximity Read ↗

Efficient expression and utilization of mutant 5 S rRNA in Saccharomyces cerevisiae.Semantic proximity Read ↗

Selection for intragenic suppressors of lethal 23S rRNA mutations in Escherichia coli identifies residues important for ribosome assembly and function.Semantic proximity Read ↗

Massive functional mapping of a 5'-UTR by saturation mutagenesis, phenotypic sorting and deep sequencing.Semantic proximity Read ↗

Eukaryotic ribosomal RNA determinants of aminoglycoside resistance and their role in translational fidelity.Semantic proximity Read ↗

Rapid in vivo exploration of a 5S rRNA neutral network.Semantic proximity Read ↗

Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly.Semantic proximity Read ↗

Genetic selection of rRNA mutations.Semantic proximity Read ↗

tRNA m7G methyltransferase Trm8p/Trm82p: evidence linking activity to a growth phenotype and implicating Trm82p in maintaining levels of active Trm8p.Semantic proximity Read ↗

Genetic probes of ribosomal RNA function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.