Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tet repressor-tetracycline interaction.

Journal of protein chemistry - 1 Oct 1996

Kaszycki P, Guz A, Drwiega M, Wasylewski Z

Abstract excerpt

Previous studies [Wasylewski et al. (1996), J. Protein Chem. 15, 45-58] have shown that the W43 residue localized within the helix-turn-helix structure domain of Tet repressor can exist in the ground state in two conformational states. In this paper we investigate the fluorescence properties of W43 of TetR upon binding of tetracycline inducer and its chemical analogs such as anhydro- and epitetracycline. Binding...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA-Binding Proteins
Share to Drug Resistance, Microbial
Share to Escherichia coli

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Kinetics

Share to Mutation

Share to Protein Binding

Share to Protein Conformation

Source

Identifiers

PMID: 8968952
DOI: 10.1007/BF01886743

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tet repressor-tetracycline interaction.PMID 8968952Read ↗

Conformational changes induced in the Tet repressor protein TetR(B) upon operator or anhydrotetracycline binding as revealed by time-resolved fluorescence spectroscopy on single tryptophan mutants.Semantic proximity Read ↗

A fluorescence study of Tn10-encoded tet repressor.Semantic proximity Read ↗

Conformational changes of the Tet repressor induced by tetracycline trapping.Semantic proximity Read ↗

Structural investigation of Tet repressor loop 154-167: a time-resolved fluorescence study of three single Trp mutants.Semantic proximity Read ↗

Teaching TetR to recognize a new inducer.Semantic proximity Read ↗

A peptide triggers allostery in tet repressor by binding to a unique site.Semantic proximity Read ↗

Two mutations in the tetracycline repressor change the inducer anhydrotetracycline to a corepressor.Semantic proximity Read ↗

Structure of the Tet repressor-tetracycline complex and regulation of antibiotic resistance.Semantic proximity Read ↗

Conformational dynamics of the tetracycline-binding aptamer.Semantic proximity Read ↗

Pressure effect on the structure of the Tet repressor protein TetR(B).Semantic proximity Read ↗

Fluorescence quenching studies of Trp repressor using single-tryptophan mutants.Semantic proximity Read ↗

Induction of single chain tetracycline repressor requires the binding of two inducers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.