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Article

Conformational dynamics of the tetracycline-binding aptamer.

Nucleic acids research - 1 Feb 2012

Förster Ute, Weigand Julia E, Trojanowski Peter, Suess Beatrix, Wachtveitl Josef

Abstract excerpt

The conformational dynamics induced by ligand binding to the tetracycline-binding aptamer is monitored via stopped-flow fluorescence spectroscopy and time-correlated single photon counting experiments. The fluorescence of the ligand is sensitive to changes within the tertiary structure of the aptamer during and after the binding process. In addition to the wild-type aptamer, the mutants A9G, A13U and A50U are...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 22053085
DOI: 10.1093/nar/gkr835
PMCID: PMC3287181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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