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Article

Essential Roles of Her2/erbB2 in Cardiac Development and Function

1 Jan 2004

Abstract excerpt

The tyrosine kinase receptor erbB2, also known in humans as Her2, is a member of the epidermal growth factor receptor (EGFR or erbB1) family, which also includes erbB3 and erbB4. The erbBs were discovered in an avian erythroblastosis tumor virus and exhibited similarities to human EGFR (Yarden and Sliwkowski, 2001). Her2/erbB2 is highly expressed in many cancer types. Its overexpression is correlated with a poor...

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Identifiers

PMID: 14749494
DOI: 10.1210/rp.59.1.1

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Source receipt: pubmed, retrieved 7 Sept 2026.

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