Genetic control of sex-dependent meiotic recombination in the major histocompatibility complex of the mouse.

doi:10.1002/j.1460-2075.1991.tb07997.x

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Article

Genetic control of sex-dependent meiotic recombination in the major histocompatibility complex of the mouse.

The EMBO journal - 1 Mar 1991

Shiroishi T, Sagai T, Hanzawa N, Gotoh H, Moriwaki K

Abstract excerpt

Meiotic recombination within the proximal region of the major histocompatibility complex (MHC) of the mouse is not random but occurs in clusters at certain restricted sites, so-called recombinational hotspots. The wm7 haplotype of the MHC, derived from the wild mouse, enhances recombination specifically during female meiosis within a fragment of 1.3 kb of DNA located between the A beta 3 and A beta 2 genes in...

Topics

Alleles
Animals
Base Sequence
Chromosome Mapping
Crosses, Genetic
DNA
Female
Major Histocompatibility Complex
Male
Meiosis
Mice
Mice, Inbred C57BL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred Strains

Molecular Sequence Data

Nucleic Acid Hybridization

Oligonucleotide Probes

Polymerase Chain Reaction

Recombination, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 2001681
DOI: 10.1002/j.1460-2075.1991.tb07997.x
PMCID: PMC452702

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2001681-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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