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Article

Molecular analysis of styrene oxide-induced hprt mutation in human T-lymphocytes.

Mutagenesis - 1 Nov 1996

Bastlová T, Podlutsky A

Abstract excerpt

Styrene-7,8-oxide (SO), the mutagenic in vivo metabolite of the widely used chemical monomer styrene, has been classified as a probable human carcinogen (IARC, 1994). We examined mutations in the hypoxanthine-guanine phosphoribosyl transferase (hprt) gene of primary human T-lymphocytes exposed to 0.2 mM SO for 6 days in vitro. PCR amplification and direct DNA sequencing were used to identify 55 SO-induced...

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Identifiers

PMID: 8962428
DOI: 10.1093/mutage/11.6.581

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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