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Article

Molecular analysis of ethylene oxide-induced mutations at the HPRT locus in human diploid fibroblasts.

Mutation research - 1 Jun 1993

Bastlová T, Andersson B, Lambert B, Kolman A

Abstract excerpt

Ethylene oxide (EtO)-induced mutations in the hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene were characterized in 28 independently derived 6-thioguanine-resistant human diploid fibroblast clones using polymerase chain reaction-based techniques and Southern blot analysis. Sequence analysis revealed one single base pair deletion and 13 base substitutions, nine of which were transversions: five AT-->TA,...

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Identifiers

PMID: 7685488
DOI: 10.1016/0027-5107(93)90021-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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