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Article

Glutathione S-transferase and N-acetyltransferase genotypes and asbestos-associated pulmonary disorders.

Journal of the National Cancer Institute - 18 Dec 1996

Hirvonen A, Saarikoski S T, Linnainmaa K, Koskinen K, Husgafvel-Pursiainen K, Mattson K, Vainio H

Abstract excerpt

BACKGROUND: Humans vary in their ability to metabolize endogenous and exogenous compounds. Glutathione S-transferases (GSTs) and N-acetyltransferases (NATs) are enzymes involved in the detoxification of hazardous agents. The GSTM1 and GSTT1 genes exhibit null (i.e., deletion) polymorphisms; in specific individuals, homozygous deletion (i.e., both copies lost) of these genes can be detected. Polymorphism of the...

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Source

Identifiers

PMID: 8961976
DOI: 10.1093/jnci/88.24.1853

Genes

NAT2
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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