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Article

Inherited GSTM1 and NAT2 defects as concurrent risk modifiers in asbestos-related human malignant mesothelioma.

Cancer research - 15 Jul 1995

Hirvonen A, Pelin K, Tammilehto L, Karjalainen A, Mattson K, Linnainmaa K

Abstract excerpt

Besides asbestos exposure, the factors that determine susceptibility to malignant mesothelioma are unknown. We evaluated the risk of GSTM1 null genotype and slow acetylation-associated NAT2 genotype for malignant mesothelioma in relation to asbestos exposure. Both the GSTM1 null genotype and the...

Topics

Adult
Aged
Arylamine N-Acetyltransferase
Asbestos
Cocarcinogenesis
Evaluation Studies as Topic
Female
Genes, Regulator
Genotype
Glutathione Transferase
Humans
Isoenzymes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Mesothelioma

Middle Aged

Polymorphism, Genetic

Risk Factors

Source

Identifiers

PMID: 7606714

Genes

GSTM1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7606714-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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