Article
Pooled analysis of NAT2 genotypes as risk factors for asbestos-related malignant mesothelioma.
International journal of hygiene and environmental health - 1 May 2009
Betti Marta, Neri Monica, Ferrante Daniela, Landi Stefano, Biava Alessandra, Gemignani Federica, Bertolotti Marinella, Mirabelli Dario, Padoan Marina, Ugolini Donatella, Botta Mario, Bonassi Stefano, Magnani Corrado, Dianzani Irma
Abstract excerpt
Malignant mesothelioma (MM) is a rare and aggressive tumor of the pleura. The most important causal factor for the development of MM is occupational exposure to asbestos. Different lines of evidence suggest a role of genetic background in MM development, as for other cancers. Two published studies observed an association between MM and N-acetyl-transferase 2 (NAT2) polymorphisms. First, a Finnish study observed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
