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Article

Synergistic effects of NAT2 slow and GSTM1 null genotypes on carcinogen DNA damage in the lung.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2010

Lee Mi-Sun, Su Li, Christiani David C

Abstract excerpt

BACKGROUND: Polymorphisms in carcinogen detoxification enzymes, NAT2 and GSTM1, have been suggested as susceptibility factors for DNA damage and lung cancer. However, little information is available on DNA adduct burden in the lung tissue and polymorphisms in NAT2 and GST genes. We investigated t...

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Share to Arylamine N-Acetyltransferase
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20501762
DOI: 10.1158/1055-9965.EPI-09-1195
PMCID: PMC2882986

Genes

NAT2
GSTM1
GSTP1
GSTT1
IMPACT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20501762-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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