Article
The glutathione S-transferase M1 (GSTM1) null genotype and benzidine-associated bladder cancer, urine mutagenicity, and exfoliated urothelial cell DNA adducts.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 1996
Rothman N, Hayes R B, Zenser T V, DeMarini D M, Bi W, Hirvonen A, Talaska G, Bhatnagar V K, Caporaso N E, Brooks L R, Lakshmi V M, Feng P, Kashyap S K, You X, Eischen B T, Kashyap R, Shelton M L, Hsu F F, Jaeger M, Parikh D J, Davis B B, Yin S, Bell D A
Abstract excerpt
Multiple studies in the general population have suggested that subjects with the glutathione S-transferase M1 (GSTM1)-null genotype, who lack functional GSTM1, are at higher risk for bladder cancer. To evaluate the impact of the GSTM1-null genotype on bladder cancer caused by occupational exposur...
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