Article
N-Acetyltransferase 2 genotype, exfoliated urothelial cells and benzidine exposure.
Frontiers in bioscience (Elite edition) - 1 Jan 2012
Ma Qing-wen, Lin Guo-fang, Chen Ji-gang, Guo Wei-Chao, Qin Yi-qiu, Golka Klaus, Shen Jian-hua
Abstract excerpt
Most studies report an association of the slow N-acetyltransferase 2 (NAT2) status with elevated bladder cancer risk. In this study, NAT2 genotypes and the decades-long records of Papanicolaou's grading of exfoliated urothelial cells in a former benzidine-exposed cohort of the Shanghai dyestuff industry (29 bladder cancer patients; 307 non-cancer cohort members, some of them presenting different grades of...
Topics
- Arylamine N-Acetyltransferase
- Benzidines
- Cohort Studies
- Genotype
- Humans
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Urothelium
