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Article

NAT2 slow acetylation and bladder cancer in workers exposed to benzidine.

International journal of cancer - 1 Jan 2006

Carreón Tania, Ruder Avima M, Schulte Paul A, Hayes Richard B, Rothman Nathaniel, Waters Martha, Grant Delores J, Boissy Robert, Bell Douglas A, Kadlubar Fred F, Hemstreet George P, Yin Songnian, LeMasters Grace K

Abstract excerpt

This study expands a previous study of NAT2 polymorphisms and bladder cancer in male subjects occupationally exposed only to benzidine. The combined analysis of 68 cases and 107 controls from a cohort of production workers in China exposed to benzidine included 30 new cases and 67 controls not previously studied. NAT2 enzymatic activity phenotype was characterized by measuring urinary caffeine metabolite ratios....

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Share to Arylamine N-Acetyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Urinary Bladder Neoplasms

Source

Identifiers

PMID: 16003747
DOI: 10.1002/ijc.21308

Genes

NAT2
GSTM1
NAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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