Article
Ethnic distribution of the glutathione transferase Mu 1-1 (GSTM1) null genotype in 1473 individuals and application to bladder cancer susceptibility.
Carcinogenesis - 1 May 1994
Lin H J, Han C Y, Bernstein D A, Hsiao W, Lin B K, Hardy S
Abstract excerpt
Polycyclic aromatic hydrocarbons, found in cigarette smoke, food and industrial materials, are potential human carcinogens. Deficiency of detoxifying enzymes, such as glutathione transferases, may affect the metabolic fates of these chemicals and raise cancer risks in exposed individuals. The GST...
Topics
- Adolescent
- Adult
- Asia
- Base Sequence
- Black People
- Disease Susceptibility
- Genotype
- Glutathione Transferase
- Humans
- Middle Aged
- Molecular Sequence Data
- Pacific Islands
- Polymerase Chain Reaction
- Urinary Bladder Neoplasms