Article
N-acetylation phenotype and genotype and risk of bladder cancer in benzidine-exposed workers.
Carcinogenesis - 1 Apr 1993
Hayes R B, Bi W, Rothman N, Broly F, Caporaso N, Feng P, You X, Yin S, Woosley R L, Meyer U A
Abstract excerpt
Several studies in subjects occupationally exposed to arylamine carcinogens have shown increased risks for bladder cancer associated with the slow acetylator phenotype. To follow up these reports, a case-control study of N-acetylation and bladder cancer risk was carried out among subjects occupationally exposed to benzidine, in benzidine dye production and use facilities in China. Thirty-eight bladder cancer...
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