Transmembrane domain mutations influence the cellular distribution of lysosomal membrane glycoprotein A.

doi:10.1006/bbrc.1996.1828

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Article

Transmembrane domain mutations influence the cellular distribution of lysosomal membrane glycoprotein A.

Biochemical and biophysical research communications - 13 Dec 1996

Wimer-Mackin S, Granger B L

Abstract excerpt

The Igp/LAMP family of mammalian and avian lysosomal type I membrane glycoproteins features short, conserved, cytosolic tails that possess lysosomal targeting information. The sequences of the adjacent transmembrane domains are also highly conserved, with six amino acids identical in all sixteen...

Topics

Amino Acid Sequence
Animals
Antigens, CD
Biomarkers
CHO Cells
Cricetinae
Lysosomal Membrane Proteins
Lysosomes
Membrane Glycoproteins
Mice
Microscopy, Fluorescence
Molecular Sequence Data
Mutation

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