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alpha(1,3)fucosyltransferases expressed by the gain-of-function Chinese hamster ovary glycosylation mutants LEC12, LEC29, and LEC30.

Archives of biochemistry and biophysics - 15 Mar 2000

Patnaik S K, Zhang A, Shi S, Stanley P

Abstract excerpt

Gain-of-function glycosylation mutants provide access to glycosylation pathways, glycosylation genes, and mechanisms that regulate expression of a glycotype. Previous studies have shown that the gain-of-function Chinese hamster ovary (CHO) mutants LEC12, LEC29, and LEC30 express an N-ethylmaleimide-resistant alpha(1, 3)fucosyltransferase (alpha(1,3)Fuc-T) activity that is not detected in CHO cells and that...

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PMID: 10700388
DOI: 10.1006/abbi.1999.1693

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VIM

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