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Article

Characterization of charge change super-repressor mutants of trp repressor: effects on oligomerization conformation, ligation and stability.

Journal of molecular biology - 22 Nov 1996

Reedstrom R J, Martin K S, Vangala S, Mahoney S, Wilker E W, Royer C A

Abstract excerpt

We have carried out a physical characterization of mutant repressor proteins of the trp repressor system of Escherichia coli by circular dichroism, chemical denaturation, and 8-anilino-1-naphthalenesulfonate binding. We have also probed the protein-protein interactions via fluorescence anisotropy and lifetime measurements and measured the thermodynamics of ligand (L-tryptophan) binding by isothermal titration...

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Identifiers

PMID: 8950265
DOI: 10.1006/jmbi.1996.0621

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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