Article
A survey of lambda repressor fragments from two-state to downhill folding.
Journal of molecular biology - 2 Apr 2010
Liu Feng, Gao Yi Gui, Gruebele Martin
Abstract excerpt
We survey the two-state to downhill folding transition by examining 20 lambda(6-85)* mutants that cover a wide range of stabilities and folding rates. We investigated four new lambda(6-85)* mutants designed to fold especially rapidly. Two were engineered using the core remodeling of Lim and Sauer, and two were engineered using Ferreiro et al.'s frustratometer. These proteins have probe-dependent melting...
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