Article
In vitro characterization of HIV type 1 biological clones from asymptomatic and symptomatic pediatric patients.
AIDS research and human retroviruses - 20 Nov 1996
Forte S E, Sullivan J L, Somasundaran M
Abstract excerpt
To investigate the mechanisms of HIV-1 cytopathogenicity, functional biological HIV-1 clones were isolated from two infected children with high viral loads in vivo. Clone HC4 was isolated from a symptomatic child and clone GC6 8-4 was isolated from an asymptomatic child. These clones were characterized for their ability to induce syncytia, and to replicate and induce single-cell death in peripheral blood-derived...
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